Endocrine Abstracts

Introduction: The Visceral Adiposity Index (VAI) has been proven to be an indicator of adipose distribution and function that indirectly expresses cardiometabolic risk, in particular in specific populations such as women with polycystic ovary syndrome, acromegaly or type 2 diabetes. Little information is known about its usefulness in the definition of cardiometabolic risk in ageing population.Objective: To study VAI in relation to metabolic and hormonal ...

Introduction: Obestatin has been proposed to have anorexigenic and anti-ghrelin action. An association has been found between ghrelin and its decline with ageing and muscle strength and functional capacity, probably mediated by GH–IGF1 axis. However, no information is available in relation to the role of obestatin in muscle strength and functional capacity.Objective: The objective was to study obestatin concentrations in relation to handgrip strengt...

Aim: To study the prevalence of metabolic syndrome (MS) and its relation with ghrelin in old men.Material and methods: Prospective-population based study (2002–2005) in which 153 independently living men older than 70 y were included. Comorbidities, physical exam, BMI, blood pressure were recorded and blood sample taken for biochemical and hormonal determinations. Metabolic syndrome was defined using IDF criteria.Results: MS w...

Background: An association of pregnancy outcomes with subclinical hypothyroidism have been reported, however, there still exists a strong controversy regarding whether subclinical hypothyroidism ought to be dealt with or not. The latest American Thyroid Association’s guideline gives support to a higher TSH upper reference range of 4 mIU/l than the one proposed a few years ago of 2.5 mIU/l for the first trimester of pregnancy, in the absence of local normal ranges of TSH. ...